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Was trying to help my cousin out getting House of the Dead working for Windows Vista. The install had many issues with the PC version. After doing some research decided to try to find the mame rom which was rather easy with a google search.

I generally use AdvanceMame but after much hassle & no luck getting it to actually run I decided to look at other options. No luck with MAME either. Finally I found a youtube video with a very snotty voice over. The answer to the question "which emulator" is on the third page of comments.

Use Nebula M2 emulator. You can read more about it & download it here: http://nebula.emulatronia.com/.