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The short answer is do something that makes you happy. Another article from CBS: http://www.cbsnews.com/stories/2010/06/13/sunday/main6577542.shtml?tag=cbsnewsTwoColUpperPromoArea
 
I think the main meat is "They made a decision to live". You can do this no matter what career path you chose. If you're an artist, make art even if it's in your spare time. The main point is find what you love & do it. Keep learning & exploring.
 
If you make good money your career allows you to get money to do the things you want to do. A career shouldn't define you as a person. If you decide you want to do something else it's not to late, man up, take the risk & make it happen. It's called a mid-life crisis & I've had several so far...